Dermal Delivery - passing the stratum corneum and beyond


Dermal Delivery - passing the stratum corneum and beyond

The Evolution of Derma Energy Serums

When we first launched Derma Energy, our vision was clear: create skincare that feels like nothing, yet delivers everything. From day one, we chose water-based, oil-free serums powered by hyaluronic acid. Instead of traditional serum bases like Capric/Caprylic Triglycerides or dimethicone—excellent in moisturisers but heavy in serums—we committed to weightlessness. The result? Effortless layering, rapid absorption, and breathable skin.

But innovation never rests.

The Next Frontier: Dermal Delivery Oil

Our next challenge was bold: to craft an oil that could do more than simply moisturise. One that could seal micro-cracks, protect the stratum corneum, and support barrier repair—while staying light and elegant on the skin.

Initially designed as a ceramide-replacement therapy, the formula soon revealed greater potential. We asked ourselves: If this oil was to be the best—how could we elevate it further?

Ceramide Replacement Therapy

As we age, our natural ceramide production declines. This weakens the skin’s barrier, making it less resilient and more prone to sensitivity. To help your skin function like its younger self, it’s essential to replenish ceramides topically. When combined with skin-mimicking oils, these lipids fortify the barrier, protecting against external stressors while preventing water loss that leads to dehydration. Pairing this with a hyaluronic acid serum delivers deep hydration, reducing feelings of dryness and restoring bounce, comfort, and vitality to the skin.

 What began as a barrier-sealing oil evolved into something entirely new: a dermal delivery oil.

From Barrier to Bioactive Delivery

Unlike conventional oils that linger on the surface, Dermal Delivery Oil actively transports water-based actives deeper into the skin. By blending penetration-enhancing esters with bioactive carrier oils, we created a system that doesn’t just sit on the skin—it integrates with it.

Penetration-Enhancing Oils & Esters

  • Ethylhexyl Stearate – silky glide, reduces barrier resistance.
  • Dimethyl Isosorbide (DMI) – improves solubility and delivery of actives like niacinamide, retinol, and ferulic acid.

Bioactive Carrier Oils

  • Squalane – biomimetic, lightweight, deeply penetrative.
  • Jojoba Oil – a wax ester that merges seamlessly with skin lipids.
  • Argan Oil – balances essential fatty acids while aiding absorption.

The Strategy for Deeper Delivery

Base Layer: Isoamyl Laurate, Coco-Caprylate, and Ethylhexyl Stearate provide spreadability and enhance penetration.

Active Carrier Oils: Squalane + Jojoba deliver natural synergy with the skin.

Booster: Dimethyl Isosorbide amplifies solubility and delivery of bioactives.

By combining Ceramide 3 with skin-mimetic oils like squalane, Dermal Delivery Oil doesn’t just coat the skin—it merges with it. Apply your water-based serums first, then seal with Dermal Delivery Oil. The payoff? Amplified penetration, maximised results, and a complexion that is radiant, resilient, and renewed.